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Brazilian vascular surgeons experience during the coronavirus (COVID-19) pandemic.
CONCLUSION: The COVID pandemic has greatly affected healthcare providers around the world. At the time of this survey, Brazilian vascular surgeons are reporting low anxiety levels during this time and are using mostly active coping mechanisms. PMID: 33019914 [PubMed - as supplied by publisher]
Source: Vascular - October 6, 2020 Category: Surgery Authors: Malgor RD, Sobreira ML, Mouawad NJ, Johnson AP, Wohlauer MV, Coogan SM, Cuff RF, Coleman DM, Sheahan MG, Woo K, Shalhub S Tags: Vascular Source Type: research

The initial experience and response of vascular surgeons in Michigan during the COVID-19 pandemic.
Conclusions: Facilities in Southeast Michigan have served as the frontline of the pandemic in the Midwest and in order to cope with the surge, rapid, and in some cases, complete restructuring of care was mandatory to effect change and attempt to deal with the emerging crisis. We describe the initial experience and response of 4 large vascular surgery health systems in Michigan to COVID-19. PMID: 33504279 [PubMed - as supplied by publisher]
Source: Vascular - January 27, 2021 Category: Surgery Authors: Mouawad NJ, Lin JC, Coleman DM, Simmons J, Kabbani LS, Cuff RF, Mansour MA Tags: Vascular Source Type: research

Effects of coronavirus disease 2019 on the Society for Vascular Surgery Vascular Quality Initiative arterial procedure registry
In the present report, we have described the abrupt pivot of Vascular Quality Initiative physician members away from standard clinical practice to a restrictive phase of emergent and urgent vascular procedures in response to the coronavirus disease 2019 (COVID-19) pandemic. The Society for Vascular Surgery Patient Safety Organization queried both data managers and physicians in May 2020 to discern the effects of the COVID-19 pandemic. Approximately three fourths of physicians (74%) had adopted a restrictive operating policy for urgent and emergent cases only.
Source: Journal of Vascular Surgery - February 3, 2021 Category: Surgery Authors: Jay P. Natarajan, Ashorne K. Mahenthiran, Daniel J. Bertges, Kristopher M. Huffman, Jens Eldrup-Jorgensen, Gary W. Lemmon Tags: COVID-19 and vascular disease Source Type: research

Hemodialysis Vascular access maintenance in the Covid-19 pandemic: Positioning paper from the Interventional Nephrology Committee of the Brazilian Society of Nephrology.
Authors: Franco RP, Costa CBS, Sousa CS, Rodrigues AT, Neves PDMM, Chula DC Abstract Vascular accesses for hemodialysis are considered the patient's lifeline and their maintenance is essential for treatment continuity. Following the example of institutions in other countries affected by the Covid-19 pandemic, the Brazilian Society of Nephrology developed these guidelines for healthcare services, elaborating on the importance of carrying out procedures for the preparation and preservation of vascular accesses. Creating definitive accesses for hemodialysis, grafts and arteriovenous fistulas are non-elective procedure...
Source: Jornal Brasileiro de Nefrologia - September 4, 2020 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Crosstalk of TLR4, vascular NADPH oxidase, and COVID-19 in diabetes: What are the potential implications?
Vascul Pharmacol. 2021 May 26:106879. doi: 10.1016/j.vph.2021.106879. Online ahead of print.ABSTRACTToll-like receptor 4 (TLR4) contributes to the pathophysiology of diabetes. This happens, at least in part, because TLR4 modulates the enzyme NADPH oxidase, a primary source of ROS in vascular structures. Increased oxidative stress disrupts key vascular signaling mechanisms and drives the progression of diabetes, elevating the likelihood of cardiovascular diseases. Recently, it has been shown that patients with diabetes are also at a higher risk of developing severe coronavirus disease 2019 (COVID-19). Given the importance o...
Source: Vascular Pharmacology - May 29, 2021 Category: Drugs & Pharmacology Authors: Amanda Almeida de Oliveira Kenia Pedrosa Nunes Source Type: research

The persistent challenges faced by vascular surgery services during the UK coronavirus pandemic: a snapshot qualitative survey
CONCLUSION: Overall, these data suggest that vascular care in the NHS is facing unprecedented pressures due to COVID-19. Vascular stakeholders will have to urgently address these issues in the coming months.STUDY REGISTRATION NUMBER: ISRCTN 80453162 (registered prospectively).PMID:34860123 | DOI:10.1308/rcsann.2021.0202
Source: Annals of the Royal College of Surgeons of England - December 3, 2021 Category: Surgery Authors: S Nandhra R A Benson Vascular and Endovascular Research Network (VERN) COVER Study Collaborative Source Type: research

Interleukin-1RA Mitigates SARS-CoV-2-Induced Inflammatory Lung Vascular Leakage and Mortality in Humanized K18-hACE-2 Mice
CONCLUSIONS: These results provide insights into the central role of NLRP3-caspase-1 pyroptotic innate immune signaling and loss of lung endothelial adherens junctions in the mechanism of acute respiratory distress syndrome induced by SARS-CoV-2. Our data show that treatment with IL-1RA during activation of inflammasome provides the ideal scenario for preventing lung vascular injury and respiratory failure in coronavirus disease 2019 (COVID-19).PMID:34496633 | DOI:10.1161/ATVBAHA.121.316925
Source: Arteriosclerosis, Thrombosis and Vascular Biology - September 9, 2021 Category: Cardiology Authors: Shiqin Xiong Lianghui Zhang Justin M Richner Jake Class Jalees Rehman Asrar B Malik Source Type: research